Impact of veno-venous collaterals on outcome after the total cavopulmonary connection (2024)

Nguyen Cong, M. B. H., Schaeffer, T., Osawa, T., Palm, J., Georgiev, S., Di Padua, C., Niedermaier, C., Heinisch, P. P., Piber, N., Hager, A., Ewert, P., Hörer, J. (2024). Impact of veno-venous collaterals on outcome after the total cavopulmonary connection. International Journal of Cardiology, 410, Artikel 132229. https://doi.org/10.1016/j.ijcard.2024.132229

Nguyen Cong, Michelle Bao Hoa ; Schaeffer, Thibault ; Osawa, Takuya et al. / Impact of veno-venous collaterals on outcome after the total cavopulmonary connection. in: International Journal of Cardiology. 2024 ; Jahrgang 410.

@article{bf90de8003fa4d4e949fc57b6570f3c6,

title = "Impact of veno-venous collaterals on outcome after the total cavopulmonary connection",

abstract = "Objective: To evaluate the prevalence of veno-venous collaterals (VVCs) after total cavopulmonary connection (TCPC) and analyze their impact on outcomes. Methods: Patients undergoing TCPC between 1994 and 2022 were evaluated. VVCs were identified using angiograms of cardiac catheterizations and their impact on outcomes was analyzed. Results: A total of 635 patients were included. Median age at TCPC was 2.3 (interquartile ranges (IQR): 1.8–3.3) years. The most frequent diagnosis was hypoplastic left heart syndrome in 173 (27.2%) patients. Prior bidirectional cavopulmonary shunt was performed in 586 (92.3%) patients at a median age of 5.3 (3.6–9.9) months. VVCs were found in 94 (14.8%) patients at a median of 2.8 (0.1–11.8) years postoperatively. The prevalence of VVCs was similar between the dominant right and left ventricle (14.7 vs. 14.9%, p = 0.967). Mean pulmonary artery pressure (16.2 vs. 16.0 mmHg, p = 0.902), left atrial pressure (5.5 vs. 5.7 mmHg, p = 0.480), transpulmonary gradient (4.0 vs. 3.8 mmHg, p = 0.554) and oxygen saturation (81.4 vs. 82.6%, p = 0.103) before TCPC were similar between patients with and without VVCs. The development of VVCs did not affect survival after TCPC (p = 0.161). Nevertheless, VVCs were a risk for the development of plastic bronchitis (PB, p < 0.001). Interventional closure of VVCs was performed in 60 (9.4%) patients at a median of 8.9 (0.6–15.1) years after TCPC, and improvement of oxygen saturation was observed in 66% of the patients. Conclusions: The prevalence of VVCs after TCPC was 15%. VVCs had no impact on survival following TCPC but were associated with a high prevalence of PB.",

keywords = "Fontan, Plastic bronchitis, Protein losing enteropathy, Single ventricle, Total cavopulmonary connection, Veno-venous collaterals",

author = "{Nguyen Cong}, {Michelle Bao Hoa} and Thibault Schaeffer and Takuya Osawa and Jonas Palm and Stanimir Georgiev and {Di Padua}, Chiara and Carolin Niedermaier and Heinisch, {Paul Philipp} and Nicole Piber and Alfred Hager and Peter Ewert and J{\"u}rgen H{\"o}rer and Masamichi Ono",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2024",

month = sep,

day = "1",

doi = "10.1016/j.ijcard.2024.132229",

language = "English",

volume = "410",

journal = "International Journal of Cardiology",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

}

Nguyen Cong, MBH, Schaeffer, T, Osawa, T, Palm, J, Georgiev, S, Di Padua, C, Niedermaier, C, Heinisch, PP, Piber, N, Hager, A, Ewert, P, Hörer, J 2024, 'Impact of veno-venous collaterals on outcome after the total cavopulmonary connection', International Journal of Cardiology, Jg. 410, 132229. https://doi.org/10.1016/j.ijcard.2024.132229

Impact of veno-venous collaterals on outcome after the total cavopulmonary connection. / Nguyen Cong, Michelle Bao Hoa; Schaeffer, Thibault; Osawa, Takuya et al.
in: International Journal of Cardiology, Jahrgang 410, 132229, 01.09.2024.

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

TY - JOUR

T1 - Impact of veno-venous collaterals on outcome after the total cavopulmonary connection

AU - Nguyen Cong, Michelle Bao Hoa

AU - Schaeffer, Thibault

AU - Osawa, Takuya

AU - Palm, Jonas

AU - Georgiev, Stanimir

AU - Di Padua, Chiara

AU - Niedermaier, Carolin

AU - Heinisch, Paul Philipp

AU - Piber, Nicole

AU - Hager, Alfred

AU - Ewert, Peter

AU - Hörer, Jürgen

AU - Ono, Masamichi

N1 - Publisher Copyright:© 2023

PY - 2024/9/1

Y1 - 2024/9/1

N2 - Objective: To evaluate the prevalence of veno-venous collaterals (VVCs) after total cavopulmonary connection (TCPC) and analyze their impact on outcomes. Methods: Patients undergoing TCPC between 1994 and 2022 were evaluated. VVCs were identified using angiograms of cardiac catheterizations and their impact on outcomes was analyzed. Results: A total of 635 patients were included. Median age at TCPC was 2.3 (interquartile ranges (IQR): 1.8–3.3) years. The most frequent diagnosis was hypoplastic left heart syndrome in 173 (27.2%) patients. Prior bidirectional cavopulmonary shunt was performed in 586 (92.3%) patients at a median age of 5.3 (3.6–9.9) months. VVCs were found in 94 (14.8%) patients at a median of 2.8 (0.1–11.8) years postoperatively. The prevalence of VVCs was similar between the dominant right and left ventricle (14.7 vs. 14.9%, p = 0.967). Mean pulmonary artery pressure (16.2 vs. 16.0 mmHg, p = 0.902), left atrial pressure (5.5 vs. 5.7 mmHg, p = 0.480), transpulmonary gradient (4.0 vs. 3.8 mmHg, p = 0.554) and oxygen saturation (81.4 vs. 82.6%, p = 0.103) before TCPC were similar between patients with and without VVCs. The development of VVCs did not affect survival after TCPC (p = 0.161). Nevertheless, VVCs were a risk for the development of plastic bronchitis (PB, p < 0.001). Interventional closure of VVCs was performed in 60 (9.4%) patients at a median of 8.9 (0.6–15.1) years after TCPC, and improvement of oxygen saturation was observed in 66% of the patients. Conclusions: The prevalence of VVCs after TCPC was 15%. VVCs had no impact on survival following TCPC but were associated with a high prevalence of PB.

AB - Objective: To evaluate the prevalence of veno-venous collaterals (VVCs) after total cavopulmonary connection (TCPC) and analyze their impact on outcomes. Methods: Patients undergoing TCPC between 1994 and 2022 were evaluated. VVCs were identified using angiograms of cardiac catheterizations and their impact on outcomes was analyzed. Results: A total of 635 patients were included. Median age at TCPC was 2.3 (interquartile ranges (IQR): 1.8–3.3) years. The most frequent diagnosis was hypoplastic left heart syndrome in 173 (27.2%) patients. Prior bidirectional cavopulmonary shunt was performed in 586 (92.3%) patients at a median age of 5.3 (3.6–9.9) months. VVCs were found in 94 (14.8%) patients at a median of 2.8 (0.1–11.8) years postoperatively. The prevalence of VVCs was similar between the dominant right and left ventricle (14.7 vs. 14.9%, p = 0.967). Mean pulmonary artery pressure (16.2 vs. 16.0 mmHg, p = 0.902), left atrial pressure (5.5 vs. 5.7 mmHg, p = 0.480), transpulmonary gradient (4.0 vs. 3.8 mmHg, p = 0.554) and oxygen saturation (81.4 vs. 82.6%, p = 0.103) before TCPC were similar between patients with and without VVCs. The development of VVCs did not affect survival after TCPC (p = 0.161). Nevertheless, VVCs were a risk for the development of plastic bronchitis (PB, p < 0.001). Interventional closure of VVCs was performed in 60 (9.4%) patients at a median of 8.9 (0.6–15.1) years after TCPC, and improvement of oxygen saturation was observed in 66% of the patients. Conclusions: The prevalence of VVCs after TCPC was 15%. VVCs had no impact on survival following TCPC but were associated with a high prevalence of PB.

KW - Fontan

KW - Plastic bronchitis

KW - Protein losing enteropathy

KW - Single ventricle

KW - Total cavopulmonary connection

KW - Veno-venous collaterals

UR - http://www.scopus.com/inward/record.url?scp=85195300114&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2024.132229

DO - 10.1016/j.ijcard.2024.132229

M3 - Article

AN - SCOPUS:85195300114

SN - 0167-5273

VL - 410

JO - International Journal of Cardiology

JF - International Journal of Cardiology

M1 - 132229

ER -

Nguyen Cong MBH, Schaeffer T, Osawa T, Palm J, Georgiev S, Di Padua C et al. Impact of veno-venous collaterals on outcome after the total cavopulmonary connection. International Journal of Cardiology. 2024 Sep 1;410:132229. doi: 10.1016/j.ijcard.2024.132229